Variational Principles and Perceptual Color Correction of Digital Images

Variational principles appear in a vast number of scientific disciplines. They often provide a 'view from above' which permits to better comprehend and analyse problems. In this paper we show how variational techniques can be used to modelise perceptual color correction of digital images. We will show that the basic human visual phenomenology defines a unique class of functionals whose minimization gives rise to color enhancement. This framework provides a unified home for noticeable models of perceptual color correction, as e.g. Retinex. This record was migrated from the OpenDepot repository service in June, 2017 before shutting down

Variational models for color image processing in the RGB space inspired by human vision Mémoire d'Habilitation a Diriger des Recherches dans la spécialité Mathématiques

La recherche que j'ai développée jusqu'à maintenant peut être divisée en quatre catégories principales : les modèles variationnels pourla correction de la couleur basée sur la perception humaine, le transfert d'histogrammes, le traitement d'images à haute gammedynamique et les statistiques d'images naturelles en couleur. Les sujets ci-dessus sont très inter-connectés car la couleur est un sujetfortement inter-disciplinaire

Off-label long acting injectable antipsychotics in real-world clinical practice: a cross-sectional analysis of prescriptive patterns from the STAR Network DEPOT study

Introduction Information on the off-label use of Long-Acting Injectable (LAI) antipsychotics in the real world is lacking. In this study, we aimed to identify the sociodemographic and clinical features of patients treated with on- vs off-label LAIs and predictors of off-label First- or Second-Generation Antipsychotic (FGA vs. SGA) LAI choice in everyday clinical practice. Method In a naturalistic national cohort of 449 patients who initiated LAI treatment in the STAR Network Depot Study, two groups were identified based on off- or on-label prescriptions. A multivariate logistic regression analysis was used to test several clinically relevant variables and identify those associated with the choice of FGA vs SGA prescription in the off-label group. Results SGA LAIs were more commonly prescribed in everyday practice, without significant differences in their on- and off-label use. Approximately 1 in 4 patients received an off-label prescription. In the off-label group, the most frequent diagnoses were bipolar disorder (67.5%) or any personality disorder (23.7%). FGA vs SGA LAI choice was significantly associated with BPRS thought disorder (OR = 1.22, CI95% 1.04 to 1.43, p = 0.015) and hostility/suspiciousness (OR = 0.83, CI95% 0.71 to 0.97, p = 0.017) dimensions. The likelihood of receiving an SGA LAI grew steadily with the increase of the BPRS thought disturbance score. Conversely, a preference towards prescribing an FGA was observed with higher scores at the BPRS hostility/suspiciousness subscale. Conclusion Our study is the first to identify predictors of FGA vs SGA choice in patients treated with off-label LAI antipsychotics. Demographic characteristics, i.e. age, sex, and substance/alcohol use co-morbidities did not appear to influence the choice towards FGAs or SGAs. Despite a lack of evidence, clinicians tend to favour FGA over SGA LAIs in bipolar or personality disorder patients with relevant hostility. Further research is needed to evaluate treatment adherence and clinical effectiveness of these prescriptive patterns

The Role of Attitudes Toward Medication and Treatment Adherence in the Clinical Response to LAIs: Findings From the STAR Network Depot Study

Background: Long-acting injectable (LAI) antipsychotics are efficacious in managing psychotic symptoms in people affected by severe mental disorders, such as schizophrenia and bipolar disorder. The present study aimed to investigate whether attitude toward treatment and treatment adherence represent predictors of symptoms changes over time. Methods: The STAR Network \u201cDepot Study\u201d was a naturalistic, multicenter, observational, prospective study that enrolled people initiating a LAI without restrictions on diagnosis, clinical severity or setting. Participants from 32 Italian centers were assessed at three time points: baseline, 6-month, and 12-month follow-up. Psychopathological symptoms, attitude toward medication and treatment adherence were measured using the Brief Psychiatric Rating Scale (BPRS), the Drug Attitude Inventory (DAI-10) and the Kemp's 7-point scale, respectively. Linear mixed-effects models were used to evaluate whether attitude toward medication and treatment adherence independently predicted symptoms changes over time. Analyses were conducted on the overall sample and then stratified according to the baseline severity (BPRS < 41 or BPRS 65 41). Results: We included 461 participants of which 276 were males. The majority of participants had received a primary diagnosis of a schizophrenia spectrum disorder (71.80%) and initiated a treatment with a second-generation LAI (69.63%). BPRS, DAI-10, and Kemp's scale scores improved over time. Six linear regressions\u2014conducted considering the outcome and predictors at baseline, 6-month, and 12-month follow-up independently\u2014showed that both DAI-10 and Kemp's scale negatively associated with BPRS scores at the three considered time points. Linear mixed-effects models conducted on the overall sample did not show any significant association between attitude toward medication or treatment adherence and changes in psychiatric symptoms over time. However, after stratification according to baseline severity, we found that both DAI-10 and Kemp's scale negatively predicted changes in BPRS scores at 12-month follow-up regardless of baseline severity. The association at 6-month follow-up was confirmed only in the group with moderate or severe symptoms at baseline. Conclusion: Our findings corroborate the importance of improving the quality of relationship between clinicians and patients. Shared decision making and thorough discussions about benefits and side effects may improve the outcome in patients with severe mental disorders

Color Image Processing

What we call the "color" of an object is the result of a very complicated and not yet fully understood mechanism that involves the interaction between the light reflected by the object surface and the eyes, and the subsequent analysis of the retinal signal by the brain. For these reasons, research into color is intrinsically multidisciplinary and can be conducted from many points of view. The contributions presented in this book reflect this spirit, ranging from rigorous mathematical models of color geometry, to the psychophysical discussion of chromatic visual illusion, passing through state-of-the-art computational models in color enhancement. The idea behind this book is to give the reader an idea of the richness and variety of the research into color, proving it to be one of the most fascinating interdisciplinary research fields in contemporary science

Ejercicios sobre límites

Recurs per als alumnes de primer d'Enginyeria, dins l'assignatura Càlcul i mètodes numèricsExercicis sobre límit

Ejercicios sobre series

Recurs per a l'assignatura Càlcul i Mètodes numèrics, Enginyeria UPFExercicis sobre sèrie